What is Zovirax made of?
Each gram of ZOVIRAX Cream, 5% contains 50 mg of acyclovir and the following inactive ingredients: cetostearyl alcohol, mineral oil, poloxamer 407, propylene glycol, sodium lauryl sulfate, water, and white petrolatum.
Can acyclovir make you depressed?
Psychiatric side-effects associated with acyclovir therapy are very rare in the medical literature. We present a case of depression with paranoid delusions in a patient with chronic lymphocytic leukemia that appeared after intravenous acyclovir treatment for herpes simplex infection.
Is Docosanol the same as acyclovir?
Are Zovirax and Abreva the Same Thing? Zovirax (acyclovir) and Abreva (docosanol cream) are antiviral medications used to treat different conditions caused by the herpes virus. Zovirax is used to treat shingles, chickenpox, and genital herpes. Abreva is used to treat cold sores/fever blisters on the face or lips.
Is acyclovir toxic?
In general, acyclovir seems to have a low toxic potential. Data from available investigations do not give support for a mutagen, teratogen or carcinogen hazard in patients receiving recommended clinical doses.
Is acyclovir poisonous?
Acyclovir is used therapeutically to treat herpes simplex, cytomegalovirus, Epstein-Barr, and varicella-Zoster. Although acyclovir is thought to be low in toxicity, it has caused an obstructive nephropathy from accumulation of crystals in renal tissue.
How toxic is acyclovir?
How much acyclovir is in Zovirax 5%?
Each gram of ZOVIRAX Ointment 5% contains 50 mg of acyclovir in a polyethylene glycol (PEG) base. Acyclovir is a white to off-white crystalline powder with the molecular formula C 8 H 11 N 5 O 3 and a molecular weight of 225.20. The maximum solubility in water at 37°C is 2.5 mg/mL. The pka’s of acyclovir are 2.27 and 9.25.
What is Zovirax ointment made of?
DESCRIPTION ZOVIRAX is the brand name for acyclovir, a synthetic nucleoside analogue active against herpes viruses. ZOVIRAX Ointment 5% is a formulation for topical administration. Each gram of ZOVIRAX Ointment 5% contains 50 mg of acyclovir in a polyethylene glycol (PEG) base.
What is the NDA for Zovirax cream?
NDA 21-478 Page 6. PRECAUTIONS General: ZOVIRAX Cream is intended for cutaneous use only and should not be used in the eye or inside the mouth or nose. ZOVIRAX Cream should only be used on herpes labialis on the affected external aspects of the lips and face.
How do you use Zovirax cold sore cream?
ZOVIRAX Cream is most effective when used early, at the start of a cold sore. For best results, apply the cream at the first sign of a cold sore (such as tingle, redness, bump, or itch). Wash your hands before using ZOVIRAX Cream. Apply ZOVIRAX Cream to clean, dry skin.