What is the mechanism of the reaction of NaI in acetone with an alkyl halide?
In the presence of sodium iodide in acetone, alkyl halides that are not sterically hindered (i.e., primary or secodary) react with the iodide nucleophile through an SN2 mechanism. The halogen of the alkyl halide serves as leaving group at the reactive sp3 hybridized carbon.
Does 1-bromobutane undergo SN1 or SN2?
This holds true in both SN1 and SN2 reactions. In SN1 reactions, a tertiary halide makes for the best kind of substrate….Nucleophilic Substitution.
| Substrate | Time for ppt to form | Heated? |
|---|---|---|
| 1-bromobutane | 55 seconds | No |
| 2-chlorobutane | 4 minutes | No |
| 2-chloro-2-methylpropane | 7 seconds | No |
| 1-chloro-2-methylpropane | 3 seconds | No |
Why 1-bromobutane react faster than 1-chlorobutane when is added with sodium iodide in acetone?
Answer and Explanation: The reaction of an alkyl halide with sodium iodide in acetone follows the SN2 S N 2 route. The 1-bromobutane react faster than 2-chlorobutane because of following reasons: 1-bromobutane is a primary alkyl halide while the 2-chlorobutane is a secondary alkyl halide.
What does NaI in acetone do?
NaI in acetone is the reagent used in Finkelstien reaction. Alkyl halides are treated with the reagent to give alkyl iodides. The important aspect of this reaction is that the reaction is driven forward because of the lower solubility of the products NaCl and NaBr in acetone even though I- is a weak nucleophile.
Why is NaI soluble in acetone?
In acetone, NaI is soluble ,as its lattice energy is lesser than the solvation energy of acetone. But NaCl or NaBr is insoluble in acetone,hence it get precipitated. So stress is exerted on the reaction equillibrium due to deposition of NaCl.
Is Bromobutane an alkyl halide?
1-bromobutane is a primary alkyl halide (primary alkyl) and therefore it is produced from bimolecular nucleophilic substitution reactions (Sn2).
Which halide will faster with sodium iodide in acetone 1-bromobutane or 1-chlorobutane?
Which halide reacted faster with sodium iodide in acetone: ]-bromobutane or ]-chlorobutane? [~bromobutane is the halide that reacted faster with sodium iodide in acetone. Moreover; Br- is the best leaving group since there esser charge density in comparison to CI- because this molecule is smaller in size.