What is olanzapine depot?
Olanzapine as pamoate monohydrate is a long-acting injectable or depot form of olanzapine. It is approved for maintenance treatment of schizophrenia in adults sufficiently stabilised during acute treatment with oral olanzapine. 2 It is given by deep intramuscular (IM) gluteal injection every 2 or every 4 weeks.
How fast does olanzapine depot work?
In most cases, symptoms appear within one hour following injection and resolve within 24 – 72 hours. Healthcare professionals are advised to discuss this potential risk with patients each time they prescribe and administer olanzapine pamoate depot injection.
How do you administer antipsychotic depot?
Most oil-based depot antipsychotic injections must be administered only into the gluteal muscle by deep intramuscular (IM) injection. The exceptions to this are flupentixol and zuclopenthixol depots which are also licensed to be administered via the lateral thigh.
How often should olanzapine be taken?
Olanzapine tablets are usually taken 1 time per day with or without food. Typically patients begin at a low dose of medicine and the dose is increased slowly over several weeks.
Can olanzapine be taken twice a day?
In conclusion, effectiveness and efficacy outcomes between once- and twice-daily dosing for risperidone and olanzapine were not significantly different. However, in view of the lower mean dose and better side effect profile, it is advisable to adhere to a once-daily dosing regimen, especially in the case of olanzapine.
How often can Zyprexa be given?
Oral olanzapine should be administered on a once-a-day schedule without regard to meals, generally beginning with 5 to 10 mg initially, with a target dose of 10 mg/day within several days.
What is depot injection used for?
Depot injections of antipsychotics are used to improve historically low adherence in patients with diseases such as schizophrenia. Different products may be administered or implanted either by a doctor or nurse, while some are designed to be administered by the patient themselves.
What does depot mean in medicine?
A depot injection is a term for an injection formulation of a medication which releases slowly over time to permit less frequent administration of a medication.
How do depots work?
A depot injection is a slow-release form of medication. The injection uses a liquid that releases the medication slowly, so it lasts a lot longer. Depot injections can be used for various types of drug, including some antipsychotics.
How often are depot injections given?
How are depot injections given? Injections are usually given every two, three or four weeks, depending on the drug. Certain antipsychotics may last for longer periods when given as a depot injection. Your injection will usually be given by a healthcare professional in a community setting.