What is NMP22 bladder check?
The NMP22 BladderChek test is an in vitro immunoassay used for the qualitative detection of NMP22 in urine. It is quick, easily available and economical, and it causes no patient discomfort. Compared with cytology, it has higher sensitivity for all stages and grades of superficial bladder cancer.
What test looks at the bladder?
Cystoscopy (sis-TOS-kuh-pee) is a procedure that allows your doctor to examine the lining of your bladder and the tube that carries urine out of your body (urethra). A hollow tube (cystoscope) equipped with a lens is inserted into your urethra and slowly advanced into your bladder.
What is a UroVysion test?
The UroVysion assay works by detecting urinary cells that have chromosomal abnormalities consistent with a diagnosis of bladder cancer. Studies have shown that UroVysion is more sensitive than urine cytology for the detection of all stages and grades of bladder cancer.
What is a positive urine cytology?
This indicates that some abnormalities were found in your urine sample cells, but they weren’t abnormal enough to be considered cancer. Suspicious. The urine cells were abnormal and might be cancerous. Positive. A positive result indicates that cancer cells were found in your urine.
How does fluorescence in situ hybridization work?
Fluorescence in situ hybridization (FISH) is a laboratory technique for detecting and locating a specific DNA sequence on a chromosome. The technique relies on exposing chromosomes to a small DNA sequence called a probe that has a fluorescent molecule attached to it.
What does a positive urine cytology test mean?
What percentage of bladder polyps are benign?
“While there are several types of benign masses that can grow in the bladder, these are uncommon and account for fewer than 1% of bladder masses,” says Khurshid Guru, MD, Chair of Roswell Park’s Department of Urology.
What is the Alere NMP22 ® bladderchek ® test?
The Alere NMP22 ® BladderChek ® Test is a fast, easy to use and non-invasive test that aids in the diagnosis and monitoring of bladder cancer, in conjunction with standard diagnostic procedures.
What is NMP22 and how does it affect bladder cancer?
Bladder cancer cells release NMP22 into urine. Even at the earliest stages of the disease, elevated levels of NMP22 can be detected using an NMP22-specific assay, making it a marker for early diagnosis and monitoring in conjunction with standard diagnostic procedures. 1 Early detection of Bladder Cancer is the key to improving chances of survival.
When should bladderchek be used?
Specifically, BladderChek should be employed every time a cystoscopy is performed, with cor … A new, relatively obscure tumor marker assay, the NMP22 BladderChek Test (Matritech, Inc.), represents a paradigm shift in the diagnosis and management of urinary bladder cancer (transitional cell carcinoma).
What is NMP22 and why is it important?
Even at the earliest stages of the disease, elevated levels of NMP22 can be detected using an NMP22-specific assay, making it a marker for early diagnosis and monitoring in conjunction with standard diagnostic procedures. 1 Early detection of Bladder Cancer is the key to improving chances of survival.