What is cutaneous medication?
Summary. Defined as a drug reaction that affects the structure or function of the skin, its appendages, or mucous membranes.
What is cutaneous reaction?
An adverse cutaneous reaction caused by a drug is any undesirable change in the structure or function of the skin, its appendages or mucous membranes and it encompass all adverse events related to drug eruption, regardless of the etiology.
What is the most common drug induced cutaneous reaction?
Common adverse skin reactions to systemic drugs include: maculopapular skin reactions; urticaria and angioedema; and the spectrum of skin lesions including fixed drug eruptions, erythema multiforme, DRESS (drug reaction with eosinophilia and systemic symptoms; also called drug hypersensitivity syndrome), Stevens- …
What are drug eruptions?
A drug eruption is an adverse skin reaction to a drug. Many medications can cause reactions, especially antimicrobial agents, sulfa drugs, NSAIDs, chemotherapy agents, anticonvulsants, and psychotropic drugs.
What medications cause skin necrosis?
Heparin and warfarin-induced skin necrosis need to be considered in this category as drug eruptions that cause dermal and epidermal necrosis. These two topics are covered in detail in this chapter. Toxic epidermal necrolysis and Stevens-Johnson syndrome cause epidermal necrosis.
What does a drug rash look like?
Drug rashes can appear as a variety of skin rashes, including pink to red bumps, hives, blisters, red patches, pus-filled bumps (pustules), or sensitivity to sunlight. Drug rashes may involve the entire skin surface, or they may be limited to one or a few body parts. Itching is common in many drug rashes.
How long does it take for a drug rash to clear up?
The best treatment for a drug rash is to stop the medication that is causing it. After discontinuing a medicine, it may take 5–10 days to see an improvement in the skin and up to 3 weeks for the rash to resolve completely.
What causes a drug eruption?
What causes drug eruptions? Immediate reactions occur within an hour of exposure to the drug and are mediated by IgE antibodies (urticaria, anaphylaxis). Delayed reactions occur between 6 hours and several weeks of first exposure to the drug. They may be mediated by IgG antibody, immune complex, or cytotoxic T cells.