What drugs are used for resistant hypertension?
The most common classes of blood pressure medicines are diuretics, calcium channel blockers, and ACE inhibitors/angiotensin receptor blockers (ARBs). Studies have shown that use of the diuretic chlorthalidone is very effective in treating hypertension.
Can resistant hypertension be treated?
Treatment of resistant hypertension is focused on the addition of fourth-line therapy where blood pressure is not controlled by treatment with three drugs, described by NICE as A+C+D: that is, an ACE inhibitor or an angiotensin II receptor blocker (A), a calcium channel antagonist (C), and a thiazide or thiazide-like …
Why is spironolactone used in resistant hypertension?
Spironolactone is recommended in patients with resistant hypertension which is defined as uncontrolled blood pressure despite three antihyperternsive drug combination including a diuretic. Spironolactone is a mineralocorticoid receptor antagonist and causes anti-androgenic side effects.
Can resistant hypertension reversed?
Resistant hypertension has several possible causes, including another underlying medical condition, but many of those causes are reversible.
What is the best medication to add to a patient with true resistant hypertension?
Spironolactone is the most effective fourth medication for treating RHTN in patients already on treatment with triple regimens that include an ACE inhibitor or ARB, amlodipine, and a thiazide-like diuretic.
How do you treat stubborn high blood pressure?
How to tame stubbornly high blood pressure
- Eat more potassium-rich fruits and vegetables. Potassium helps lower blood pressure.
- Try not to eat processed and restaurant-prepared foods. These foods can be loaded with sodium, which raises blood pressure.
- Go easy on alcohol.
- Check over-the-counter medications.
How do you treat resistant hypertension naturally?
Monitoring and treatment of resistant hypertension
- Eating a well-balanced, low-salt diet.
- Limiting alcohol.
- Enjoying regular physical activity.
- Maintaining a healthy weight.
- Managing stress.
- Taking your medications properly.
What is the difference between refractory and resistant?
Refractory hypertension is a recently proposed phenotype of antihypertensive treatment failure. As such it represents an extreme subtype of resistant or difficult-to-treat hypertension. Resistant hypertension is relatively common with an estimated prevalence of 10–20% of treated hypertensive patients.
How common is treatment resistant hypertension?
Resistant hypertension, defined as failure to achieve goal blood pressures in patients taking optimal or maximum tolerated doses of three or more antihypertensive drugs, is estimated to occur in about 25% of hypertensive patients on treatment.
What happens if your blood pressure won’t go down?
As the arteries become narrower and less flexible, the heart has to work harder to move blood through the body. Uncontrolled high blood pressure can lead to stroke, heart attack, heart failure and other heart conditions; cause damage to your kidneys, memory and vision; and contribute to erectile dysfunction.
What causes treatment resistant hypertension?
Treatment resistance can be attributed to poor adherence to antihypertensive drugs, excessive salt intake, physician inertia, inappropriate or inadequate medication, and secondary hypertension.
Why won’t my blood pressure go down even with medication?
With complicated dosing schedules, people can forget to take medications or not take the correct doses at the correct times. Also, other drugs can interfere with blood pressure control, including pain relievers (NSAIDs), oral contraceptives and nasal decongestants.