What does a high steatosis score mean?
Fatty Liver/Steatosis A CAP score that falls anywhere between 238 to 260 dB/m represents 11-33% fatty change in the liver. A CAP score that falls anywhere between 260 to 290 dB/m represents 34-66% fatty change in the liver. A CAP score that is 290 dB/m or higher represents over 67% fatty change in the liver.
What is a FibroSure score?
FibroTest, known as FibroSure in the US, is a biomarker test that uses the results of six blood serum tests to generate a score that is correlated with the degree of liver damage in people with a variety of liver diseases. FibroTest has the same prognostic value as a liver biopsy.
How do you interpret a fib 4 score?
The FIB-4 index is a new noninvasive test for the assessment of liver fibrosis. A score of <1.45 and >3.25 enables the correct identification of patients who have moderate or significant fibrosis, respectively, and could avoid LB examination.
How many stages of fibrosis are there?
There are five stages (F0: no scarring (no fibrosis); F1: minimal scarring; F2: scarring has occurred and extends outside the liver area (significant fibrosis); F3: fibrosis spreading and forming bridges with other fibrotic liver areas (severe fibrosis); F4: cirrhosis or advanced scarring).
How is FibroSure calculated?
The overall FibroSure score is calculated using a proprietary formula that combines the results of all 6 markers in addition to patient age and gender. The FibroSure report includes the results of the individual tests, the computed fibrosis score (which is the most helpful), and an associated fibrosis stage (F0-F4).
Is FibroSure accurate?
The testing algorithm using Fibrosure was the most accurate non-invasive strategy with a sensitivity, specificity, and overall accuracy of 84 %, 87 %, and 86 %, respectively.
What is a high fib-4 score?
The scoring system creates a score – <1.45 has a negative predictive value of over 90% for advanced liver fibrosis of multiple aetiologies (1)(2). A score of >3.25 has a positive predictive value of 65% for advanced fibrosis with a specificity of 97%.
What is a good AST ALT ratio?
A normal AST:ALT ratio should be <1. In patients with alcoholic liver disease, the AST:ALT ratio is >1 in 92% of patients, and >2 in 70%. AST:ALT scores >2 are, therefore, strongly suggestive of alcoholic liver disease and scores <1 more suggestive of NAFLD/NASH.