What causes transient Erythroblastopenia?
Studies suggest that TEC may be caused by certain viral illnesses, serum inhibitors against erythroid progenitor cells, and cell-mediated suppression of erythropoiesis. Viruses that have been implicated include parvovirus B19, human herpes virus type 6, and echovirus 11; however, in most cases no virus is detected.
What is a TEC test?
Abstract. Purpose: The diagnosis of transient erythroblastopenia of childhood (TEC) is usually straightforward, with temporary cessation of red blood cell production resulting in normocytic normochromic anemia, reticulocytopenia, and bone marrow erythroblastopenia.
What is TEC in Haematology?
Specialty. Pediatrics, hematology. Transient erythroblastopenia of childhood (TEC) is a slowly developing anemia of early childhood characterized by gradual onset of pallor.
What is transient aplastic crisis?
Transient aplastic crisis (TAC) is a temporary cessation of red cell production by the bone marrow leading to severe anemia, most commonly seen in patients predisposed to increased RBC destruction.
What disease or disorder does Erythrocytopenia lead?
Anemia. Chronic infection is associated with the anemia of chronic illness. Acute infection, particularly viral infection, can produce transient bone marrow aplasia or selective transient erythrocytopenia.
Does anemia come on suddenly?
It can occur suddenly, or it can come on slowly and worsen over time. It can be mild or severe.
Why is red blood cell count important?
Red blood cells help carry oxygen throughout the body. Doctors measure your red blood cell count to help diagnose medical conditions and learn more about your health. A high red blood cell count means the number of red blood cells in your bloodstream is higher than normal.
What is Blackfan Diamond anemia?
In Diamond-Blackfan anemia, the bone marrow malfunctions and fails to make enough red blood cells, which carry oxygen to the body’s tissues. The resulting shortage of red blood cells (anemia ) usually becomes apparent during the first year of life.
What virus causes aplastic?
Topic Overview. If a person with sickle cell disease is infected with parvovirus, the virus that causes fifth disease in children, an aplastic crisis may develop. Bone marrow suddenly stops producing red blood cells, which results in sudden and severe anemia.