What causes gastric mucosal atrophy?
Atrophy of the gastric mucosa is the endpoint of chronic processes, such as chronic gastritis associated with Helicobacter pylori (H. pylori) infection, other unidentified environmental factors, and autoimmunity directed against gastric glandular cells[1].
What is non atrophic gastritis?
Chronic non-atrophic gastritis (CNG) is characterized by the infiltration of chronic inflammatory cells and the absence of atrophy in the mucosal layer.
What is diffuse atrophic mucosa?
Atrophic gastritis is a histopathologic entity characterized by chronic inflammation of the gastric mucosa with loss of the gastric glandular cells and replacement by intestinal-type epithelium, pyloric-type glands, and fibrous tissue.
What is a trophic gastritis?
What is atrophic gastritis? Atrophic gastritis (AG) develops when the lining of the stomach has been inflamed for several years. The inflammation is most often the result of a bacterial infection caused by the H. pylori bacterium.
What is autoimmune metaplastic atrophic gastritis?
Autoimmune metaplastic atrophic gastritis — AMAG is a form of metaplastic (chronic) atrophic gastritis that results in the replacement of the normal oxyntic mucosa in the gastric corpus by atrophic and metaplastic mucosa, leading to a corpus predominant atrophic gastritis, reduced or absent acid and pepsin production.
Can Vitamin B12 deficiency cause gastritis?
Atrophic gastritis was more common in individuals with B12 deficiency, while superficial gastritis was the most common finding in controls. The incidence of intestinal metaplasia (in the antrum) was similar in the individuals with or without B12 deficiency.
Is atrophic gastritis the same as chronic gastritis?
Atrophic gastritis is a development of chronic gastritis and the symptoms depend on the specific cause of the condition. For example, atrophic gastritis if due to chronic gastritis caused by H. pylori bacteria may often not cause many, possibly not even any symptoms.
What is diffuse mucosa?
A diffuse granular mucosal pattern, produced by a reticular network of radiolucent foci 0.5 to 1 mm in diameter, was identified in 39 out of 46 consecutive patients with Crohn disease of the small intestine. Resected specimens demonstrated that this pattern represented wide, blunted villi with lymphocytic infiltration.
What is the difference between Type A and Type B chronic gastritis?
Type A gastritis, which involves the fundus, is associated with pernicious anemia, antibodies to parietal cells, and autoimmune conditions of other organs. Type B gastritis, which is much more common, appears to mainly affect the antrum, autoimmune phenomena are absent, and it has been considered idiopathic.
Is gastritis a autoimmune disease?
Autoimmune atrophic gastritis is considered an autoimmune disorder. In people who are affected by this condition, the immune system mistakenly attacks the healthy cells of the stomach lining.
What is the difference between gastritis and atrophic gastritis?
Gastritis is the medical term for stomach inflammation. Atrophic gastritis is a chronic form of gastritis. Doctors mostly find inflammation in the mucous membrane of a person’s stomach lining. This leads to various digestive problems.