What are the main hazards of 4 nitrobenzoic acid?
EC Number: 200-526-2
ACUTE HAZARDS | FIRE FIGHTING | |
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FIRE & EXPLOSION | Combustible. Gives off irritating or toxic fumes (or gases) in a fire. Risk of explosion on contact with potassium hydroxide. | Use foam, dry powder, carbon dioxide. |
Is nitrobenzoic acid soluble in water?
Insoluble in water. O-NITROBENZOIC ACID is incompatible with strong oxidizing agents.
Is P-nitrobenzoic acid?
4-Nitrobenzoic acid is an organic compound with the formula C6H4(NO2)CO2H. It is a pale yellow solid. It is a precursor to 4-nitrobenzoyl chloride, the precursor to the anesthetic procaine and folic acid….CHEBI:262350.
Synonyms | Sources |
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p-nitrobenzoic acid | ChemIDplus |
p-nitrodracylic acid | NIST Chemistry WebBook |
How do you synthesize P-nitrobenzoic acid?
p-Nitrobenzoic acid can be prepared by the oxidation of p-nitrotoluene with nitric acid,1 chromic acid,2 permanganates,3 and electrolytically.
What is the density of 4 nitrobenzoic acid?
1.58 g/cm³4-Nitrobenzoic acid / Density
Is 4 nitrobenzoic acid soluble in ether?
One gram dissolves in 2380 mL water, 110 mL alcohol, 12 mL methanol, 150 mL chloroform, 45 mL ether, 20 mL acetone; slightly soluble in benzene, carbon disulfide; insol in petroleum ether.
Is 4 nitrobenzoic acid polar?
4-nitrobenzoic acid is a nitrobenzoic acid having the nitro group at the 4-position. It derives from a benzoic acid. It is a conjugate acid of a 4-nitrobenzoate….3.1Computed Properties.
Property Name | Property Value | Reference |
---|---|---|
Topological Polar Surface Area | 83.1 Ų | Computed by Cactvs 3.4.8.18 (PubChem release 2021.05.07) |
What is the melting point of 4 nitrobenzoic acid?
458.6°F (237°C)4-Nitrobenzoic acid / Melting point
What is the structure of nitrobenzoic acid?
4-Nitrobenzoic acid
PubChem CID | 6108 |
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Structure | Find Similar Structures |
Chemical Safety | Laboratory Chemical Safety Summary (LCSS) Datasheet |
Molecular Formula | C7H5NO4 or HOOCC6H4NO2 |
Synonyms | 4-NITROBENZOIC ACID p-Nitrobenzoic acid 62-23-7 Benzoic acid, 4-nitro- Nitrodracylic acid More… |
How is benzocaine synthesized industrially from p-nitrobenzoic acid?
Principle: In step 1 common reduction of aromatic para-nitrobenzoic acid by tin and hydrochloric acid to para-aminobenzoic acid and in step 2 esterification of para-aminobenzoic acid by sulphuric acid and ethanol to benzocaine occurring called Fischer esterification.
What is principle of synthesis of benzocaine?
The classic, optimal way of benzocaine synthesis is the reduction of the nitro group of the ethyl ester of 4-nitrobenzoic acid to benzocaine by hydrogen, which generates directly in the reaction medium by the reaction of iron filings with dilute acids [24–26].
How do you synthesize benzocaine from P nitrotoluene?