How do you infuse amiodarone?
The current dosing recommendation for intravenous amiodarone is to give ≈1000 mg over the first 24 hours. The initial infusion should contain 3 mL of amiodarone injection (150 mg) in 100 mL D5W (concentration of 1.5 mg/mL). One should infuse this 100 mL over 10 minutes (15 mg/min) for a total of 150 mg.
How do you give amiodarone bolus?
Use of a 0.2 or 0.22 micron filter is recommended for intermittent and continuous infusions.
- Bolus doses: in 100 ml D5W over 10 min (maximum infusion rate 30 mg/min)
- Continuous infusion: in 500 ml D5W (in non PVC bag) over 24 hours.
- Cardiac Arrest: First dose: Give 300 mg (6 mL) IV direct UNDILUTED.
What pharmaceutical company makes amiodarone?
Apr. 16, 2018, Greenville, N.C.: Mayne Pharma Group Limited (ASX: MYX) is pleased to announce the launch of amiodarone tablets, 200mg, in the United States. Amiodarone is a generic alternative to Cordarone® tablets, indicated for life-threatening recurrent ventricular arrhythmia.
Can amiodarone be mixed in normal saline?
Amiodarone is incompatible with saline and should be administered solely in 5% dextrose solution.
Does premixed amiodarone need a filter?
Use an in-line filter during administration. Please see full NEXTERONE (amiodarone) Prescribing Information for dosage and administration.
When do you stop amiodarone drip?
Intravenously administered amiodarone causes heart block or bradycardia in 4.9 percent of patients and hypotension in 16 percent. 2 If these conditions occur, infusion of the drug should be discontinued, or the rate of infusion should be reduced.
What tubing is used for amiodarone?
Amiodarone adsorbs to polyvinyl chloride (PVC) tubing, but all of the clinical experience has been with PVC tubing and the concentrations and rates of infusion provided in DOSAGE AND ADMINISTRATION reflect dosing in these studies.
What do you mix amiodarone with?
To prepare Amiodarone for an IV infusion, mix with D5W and give through an in-line filter. Alternatively, it is NOT necessary to dilute amiodarone for IV push administration and a filter is not necessary. When infusions exceed 2 hours, amiodarone can absorb into the plastic used for standard IV bags.
How fast do you push amiodarone?
Dosing protocols administering the bolus dose in smaller aliquots of 1 to 2 mg/kg/dose IV over 5 to 10 minutes have been recommended in order to reduce patient exposure to plasticizers, such as DEHP, which may be leached out of IV tubing, including polyvinyl chloride (PVC) tubing, by certain formulations of amiodarone.
How fast do you push amiodarone in a code?
This can often be at a rate of 1mg/min over 6 hours, then 0.5 mg/min for 18 hours, or as the physician prescribes, based upon the patient’s clinical condition. CAUTION: Amiodarone drips MUST be mixed and administered from a glass container, as the medication will be absorbed into the plastic.
What is the generic drug for amiodarone?
What Is Cordarone? Cordarone (amiodarone) is an antiarrhythmic drug used for many serious arrhythmias of the heart including ventricular fibrillation, ventricular tachycardia, atrial fibrillation, and atrial flutter. Cordarone is available in generic form.