What strengths does Dilantin come in?
Loading Dose Initially, one gram of DILANTIN (extended phenytoin sodium capsules, USP) is divided into three doses (400 mg, 300 mg, 300 mg) and administered at two-hour intervals.
What is Dilantin 100 mg used for?
DILANTIN is a prescription medicine used to treat certain types of seizures called tonic-clonic (grand mal) and psychomotor (temporal lobe) seizures and to prevent and treat seizures that happen during or after brain surgery.
Can Dilantin be dosed once daily?
Once-a-day dosage: A major problem in motivating noncompliant patients may also be lessened when the patient can take this drug once a day. However, patients should be cautioned not to miss a dose, inadvertently. Only extended phenytoin sodium capsules are recommended for once-a-day dosing.
What are the side effects of Dilantin 100 mg?
Headache, nausea, vomiting, constipation, dizziness, feeling of spinning, drowsiness, trouble sleeping, or nervousness may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
What is Dilantin used for other than seizures?
In some cases, anticonvulsant medications like Dilantin may also be used in the treatment of mood disorders, such as for certain forms of bipolar disorder.
What happens when Dilantin level is too high?
The neurotoxic effects are concentration dependent and can range from mild nystagmus to ataxia, slurred speech, vomiting, lethargy and eventually coma and death. Paradoxically, at very high concentrations, phenytoin can lead to seizures. Symptoms correlate well with the unbound plasma phenytoin concentration.
What is the normal range for Dilantin levels?
The therapeutic range is 10-20 mcg/mL. Total phenytoin levels (mcg/mL) and typical corresponding signs and symptoms are as follows: Lower than 10 – Rare.
How much Dilantin is an overdose?
Twenty to 30 mg/L: Nystagmus. Thirty to 40 mg/L: Ataxia, slurred speech, tremor, nausea, and vomiting. Forty to 50 mg/L: Lethargy, confusion, hyperactivity. Greater than 50 mg/L: Coma and seizures.
What is a sub therapeutic level for Dilantin?
The therapeutic range is 10-20 mcg/mL. Total phenytoin levels (mcg/mL) and typical corresponding signs and symptoms are as follows: Lower than 10 – Rare. Between 10 and 20 – Occasional mild nystagmus.
What should you not take with Dilantin?
Avoid taking antacids at the same time you take Dilantin. Antacids can make it harder for your body to absorb the medication.
What is a normal Dilantin level?
The therapeutic ranges for most adults have been established at 10.0-20.0 mcg/mL for total phenytoin (bound plus unbound) and 1.0-2.0 mcg/mL for free phenytoin (unbound only). This reference range for unbound phenytoin (free) was established based on an assumed 10% unbound drug fraction.
What are the safe levels for Dilantin?
If you take Dilantin during pregnancy,your baby is at risk for serious birth defects.
The suitable blood concentration of Dilantin usually ranges from 10 micrograms per milliliter to 20 micrograms per milliliter. When the level surpasses or reaches 30 micrograms per milliliter, then it can cause Dilantin toxicity in patients.
What is Dilantin, and how is it used and abused?
What Is Dilantin, and How Is It Used and Abused? Dilantin (phenytoin) is one of the first anticonvulsant medications as it was developed in the early 1900s. Its major uses are for the prevention of seizures, particularly tonic-clonic seizures (that affect the entire brain) or partial seizures (seizures that affect only half of the brain or one
Does Dilantin cause high blood pressure?
• high blood sugar levels • lymphadenopathy, a condition of Dilantin has been known to cause abnormalities and malignancies in the newborns, water retention and high blood pressure • some medicines used to treat stomach or duodenal ulcers, such