How do you give IV push to famotidine?
IV Push: To prepare famotidine intravenous solutions, aseptically dilute 2mL of famotidine injection (solution containing 10mg/mL) with 0.9% Sodium Chloride Injection or other compatible intravenous solution (see Stability) to a total volume of either 5 mL or 10 mL, and inject over a period of not less than 2 minutes.
Is IV PEPCID compatible with lactated ringers?
When added to or diluted with most commonly used intravenous solutions, e.g., Water for Injection, 0.9% Sodium Chloride Injection, 5% and 10% Dextrose Injection, or Lactated Ringer’s Injection, diluted PEPCID Injection is physically and chemically stable (i.e., maintains at least 90% of initial potency) for 7 days at …
Can famotidine go IV?
PEPCID (famotidine) Injection is supplied as a sterile concentrated solution for intravenous injection. Each mL of the solution contains 10 mg of famotidine and the following inactive ingredients: L-aspartic acid 4 mg, mannitol 20 mg, and Water for Injection q.s. 1 mL.
Does famotidine interact with?
Famotidine has no known severe interactions with any drugs.
What is the maximum concentration that famotidine can be administered IV push?
While famotidine may be effective in patients with less severe GERD, proton pump inhibitors (PPIs) offer more rapid symptom relief and better healing. 0.25 mg/kg/dose IV every 12 hours (Max: 40 mg/day) is the FDA-approved dosage; doses up to 0.5 mg/kg/dose IV every 12 hours have been used.
What is Pepcid IV used for?
It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as cough that doesn’t go away, stomach pain, heartburn, and difficulty swallowing. Famotidine belongs to a class of drugs known as H2 blockers.
What is not compatible with lactated ringers?
Eight drugs, ciprofloxacin, cyclosporine, diazepam, ketamine, lorazepam, nitroglycerin, phenytoin, and propofol, were found to be incompatible and should not be administered with LR.
When is lactated ringers contraindicated?
Lactate administration is contraindicated in severe metabolic acidosis or alkalosis, and in severe liver disease or anoxic states which affect lactate metabolism.
Why is PEPCID given IV?
It relieves symptoms such as cough that doesn’t go away, stomach pain, heartburn, and difficulty swallowing. Famotidine belongs to a class of drugs known as H2 blockers. This form of famotidine is given by vein and is used to treat these conditions for a short time when you cannot take the medication by mouth.
What can you not mix with famotidine?
Some affected products include atazanavir, dasatinib, delavirdine, certain azole antifungals (such as itraconazole, ketoconazole), levoketoconazole, pazopanib, among others. Do not take this medication with other products that contain famotidine or other H2 blockers (cimetidine, nizatidine, ranitidine).
Can I take famotidine with Betahistine?
The therapeutic efficacy of Betahistine can be decreased when used in combination with Famotidine.
Is famotidine compatible with dextrose?
For adults, dilute 40 mg of famotidine in 250 mL of 5% Dextrose injection or 0.9% Sodium Chloride injection or other compatible solution. The diluted solution is stable for up to 48 hours at room temperature.
Is famotidine compatible with smoflipid?
Smoflipid was tested with 2 different concentrations of famotidine due to manufacturer-reported incompatibility with famotidine 2.5 mg/mL. However, in our simulated Y-site mixing study, famotidine at 0.25 and 2.5 mg/mL had PFAT5 values below the USP <729> limit.
How do you make a famotidine IV push?
IV Push: To prepare famotidine intravenous solutions, aseptically dilute 2mL of famotidine injection (solution containing 10mg/mL) with 0.9% Sodium Chloride Injection or other compatible intravenous solution (see Stability) to a total volume of either 5 mL or 10 mL, and inject over a period of not less than 2 minutes.
How do you take famotidine 20 mg?
Dilute 20 mg of famotidine injection to a total of 5 or 10 mL with 0.9% Sodium Chloride injection or other compatible solution to give concentrations of 4 or 2 mg/mL, respectively. Inject appropriate dose over >= 2 minutes and at a rate <= 10 mg/minute.
Does famotidine need to be refrigerated?
If solution freezes, bring to room temperature; allow sufficient time to solubilize all the components. It’s recommended that if not used immediately after preparation, diluted solutions of famotidine injection should be refrigerated and used within 48 hours FOR INTRAVENOUS USE ONLY AFTER DILUTION.