Does metoclopramide help migraines?
Metoclopramide (Reglan) is a dopamine and serotonin antagonist that is used off-label to treat migraine headaches in the emergency department (ED). Because metoclopramide is an antiemetic, it makes sense that this drug can be effective for nausea and vomiting associated with certain types of headaches.
Can you take metoclopramide for headaches?
Conclusion: Metoclopramide is efficacious in the treatment of both the pain and nausea of migraine headache. This is a direct action that is not dependent on the concomitant administration of another agent.
Which drug is used as a first-line therapy for severe migraines?
Acetaminophen and nonsteroidal anti-inflammatory drugs are first-line treatments for mild to moderate migraines, whereas triptans are first-line treatments for moderate to severe migraines.
What is the IV treatment for migraine headaches?
Magnesium: Magnesium sulfate administered intravenously has successfully treated patients who have migraine with aura. In migraine patients without aura, magnesium did not reduce pain or nausea, but it did decrease sensitivity to light and sound.
When should I take metoclopramide for migraines?
Take two tablets or two sachets at the start of a migraine attack. If your symptoms continue, take two further tablets or sachets after four hours, and a further two tablets or sachets four hours later if necessary.
What’s in the migraine cocktail?
The exact medications used in a migraine cocktail can vary, but it typically includes triptans, NSAIDs, and antiemetics. A migraine cocktail is also available in OTC medication. OTC products usually contain aspirin, acetaminophen, and caffeine.
What is given in ER for migraine?
Nonsteroidal anti-inflammatory drugs, antiemetic medications, diphenhydramine, dexamethasone, and intravenous fluids all have shown benefit for treating acute migraine in the ED. Their effect is greater when they are all administered up front as opposed to being delivered in a stepwise pattern throughout the ED stay.