What are lipoproteins and its classification?
There are four major classes of circulating lipoproteins, each with its own characteristic protein and lipid composition. They are chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL).
What are lipoproteins and their function?
A lipoprotein is a biochemical assembly whose primary function is to transport hydrophobic lipid (also known as fat) molecules in water, as in blood plasma or other extracellular fluids.
What are the three key lipoproteins?
The main types of lipoproteins that are analyzed in a lipid panel include very low-density lipoproteins (VLDS), low-density lipoproteins (LDL), and high-density lipoproteins (HDL).
What type of lipid is lipoprotein?
Lipoproteins are complex particles that have a central hydrophobic core of non-polar lipids, primarily cholesterol esters and triglycerides. This hydrophobic core is surrounded by a hydrophilic membrane consisting of phospholipids, free cholesterol, and apolipoproteins (Figure 1).
What are the 5 types of lipoproteins?
Plasma lipoproteins are separated by hydrated density; electrophretic mobility; size; and their relative content of cholesterol, triglycerides, and protein into five major classes: chylomicrons, very-low-density lipoproteins (VLDL), intermediate-density lipoproteins (IDL), low-density lipoproteins (LDL), and high- …
What are lipoproteins Slideshare?
LIPOPROTEINS Definition: A lipoprotein is a biochemical assembly that contains both proteins and lipids , bound to the proteins , which allow fats to move through the water inside and outside cells. 3-Chylomicron (largest; lowest in density due to high lipid/protein ratio; highest in triacylglycerols as % of weight).
What is the clinical significance of lipoproteins and apolipoproteins?
Apolipoproteins (apo) play very important roles in the synthesis and catabolism of plasma lipoproteins, in lipid transport, and as activators of certain enzymes associated with lipid and lipoprotein metabolism. They are also involved in various metabolic states or diseases.
What means lipoprotein?
Lipoproteins are substances made of protein and fat that carry cholesterol through your bloodstream. High-density lipoprotein (HDL), or “good” cholesterol. Low-density lipoprotein (LDL), or “bad” cholesterol.
What is lipoprotein Slideshare?
Are triglycerides lipoproteins?
Triglycerides are the most common form of fat in the bloodstream. They consist of three fatty acid chains linked by a molecule called glycerol. These fatty particles can’t move freely through the watery bloodstream. So they combine with cholesterol and protein to form lipoproteins.
What is the clinical significance of lipoproteins?
Lipoprotein(a) [Lp(a)] is a unique lipoprotein that has emerged as an independent risk factor for developing vascular disease. Plasma Lp(a) levels above the common cut-off level of 300 mg/L place individuals at risk of developing heart disease particularly if combined with other lipid and thrombogenic risk factors.