What is neuralgic amyotrophy?
Hereditary neuralgic amyotrophy is a disorder characterized by episodes of severe pain and muscle wasting (amyotrophy) in one or both shoulders and arms. Neuralgic pain is felt along the path of one or more nerves and often has no obvious physical cause.
What causes neuralgic amyotrophy?
The exact cause of PTS is unknown (idiopathic), but – just as in HNA – the disorder is believed to be caused by a combination of an underlying susceptibility, mechanical factors (such as strain on the arm or shoulder) that weaken the blood nerve barrier and a final immune “trigger” that sets of the attacks.
How can you get hereditary neuralgic amyotrophy?
Hereditary neuralgic amyotrophy can be caused by mutations in the SEPT9 gene. Mutations in the SEPT9 gene are inherited in an autosomal dominant manner. Treatment for this condition is typically focused on pain management.
What is Parson Turner syndrome?
Parsonage-Turner syndrome (PTS) is an uncommon neurological disorder characterized by rapid onset of severe pain in the shoulder and arm. This acute phase may last for a few hours to a few weeks and is followed by wasting and weakness of the muscles (amyotrophy) in the affected areas.
Is brachial neuritis curable?
While there is currently no treatment for the underlying causes of brachial neuritis, the condition usually heals on its own within a few months or a couple years. Treatments for brachial neuritis typically focus on pain management in the shoulder and/or arm.
Is brachial neuritis hereditary?
Hereditary brachial plexus neuropathy (HBPN) is an autosomal dominant disorder with periodic attacks of unilateral or asymmetrical pain, weakness, atrophy, and sensory alterations of the shoulder girdle and upper limb muscles, usually attributed to involvement of proximal upper limb nerves or the brachial plexus.
What is brachial Plexitis?
Brachial plexitis is a condition characterized by acute onset of shoulder pain followed by weakness and/or sensory loss of the shoulder and/or upper extremity. Dreschfeld first described it in 1887. Multiple reports further described the condition.
What is brachial Plexopathy?
Brachial plexopathy is a form of peripheral neuropathy. It occurs when there is damage to the brachial plexus. This is an area on each side of the neck where nerve roots from the spinal cord split into each arm’s nerves.
What is hereditary neuralgic amyotrophy?
Hereditary neuralgic amyotrophy is a type of nervous system disease that affects the group of nerves that control movement in the arms and shoulders called the brachial plexus. Signs and symptoms usually begin around 20 years of age and may include episodes of severe pain and muscle loss in one or both shoulders and arms.
What are the diagnostic challenges of neuralgic amyotrophy?
Another diagnostic challenge occurs at the onset of neuralgic amyotrophy, when the patient first presents with severe shoulder pain prior to the development of severe forequarter muscle weakness and atrophy and prior to the recognition that the severe shoulder pain is monophasic in its timing.
Does neuralgic amyotrophy affect lower extremity?
Lower extremity involvement. Although the literature reports that lower extremity muscles may occasionally be affected by a bout of hereditary neuralgic amyotrophy (61), we did not note lower extremity muscle involvement in any of our 281 patients with the sporadic form of neuralgic amyotrophy (23).
What are the signs and symptoms of neuralgic amyotrophy (flulike illness)?
Important points. The patient demonstrates the full triad of neuralgic amyotrophy (flulike illness, severe right shoulder pain, muscle atrophy). The distribution of the sensory and motor examination abnormalities suggested an upper plexus lesion or multiple mononeuropathies receiving intermediate innervation via the upper plexus.