Is erythromycin a beta-lactam antibiotic?
Beta-lactam antibiotics, the tetracyclines, chloramphenicol, erythromycin, clindamycin, metronidazole, and the quinolones.
What are lactam antibiotics?
β-lactam antibiotics are bactericidal, and act by inhibiting the synthesis of the peptidoglycan layer of bacterial cell walls. The peptidoglycan layer is important for cell wall structural integrity, especially in Gram-positive organisms, being the outermost and primary component of the wall.
What is an example of ß lactam antibiotics?
β-lactam antibiotics, including penicillins and cephalosporins, inhibit platelet aggregation responses, and some can induce a bleeding diathesis when given in high doses. These include carbenicillin, penicillin G, ticarcillin, ampicillin, nafcillin, cloxacillin, mezlocillin, oxacillin, and piperacillin.
What is a lactam group?
A lactam is a cyclic amide, formally derived from an amino alkanoic acid. The term is a portmanteau of the words lactone + amide.
What kind of drug is erythromycin?
Erythromycin belongs to the class of medicines known as macrolide antibiotics. It works by killing bacteria or preventing their growth. This product is available in the following dosage forms: Capsule, Delayed Release.
Is methicillin a beta-lactam?
Methicillin, a β-lactam antibiotic, acts by inhibiting penicillin-binding proteins (PBPs) that are involved in the synthesis of peptidoglycan, an essential mesh-like polymer that surrounds the cell.
Is levofloxacin a beta-lactam?
PNEUMONIA. The beta-lactam antibiotics are not the preferred first-line agents for empiric outpatient treatment of community-acquired pneumonia. 24 Quinolone antibiotics with enhanced S. pneumoniae coverage (e.g., levofloxacin [Levaquin]) or macrolide antibiotics are preferred.
Can lactam be a primary amide?
A primary (1°) amide has nitrogen attached to a single carbon; a secondary (2°) amide has the nitrogen attached to two carbons; a tertiary (3°) amide has the nitrogen attached to three carbons. A cyclic amide is called a lactam.
What kind of infections does erythromycin treat?
Erythromycin is used to prevent and treat infections in many different parts of the body, including respiratory tract infections, skin infections, diphtheria, intestinal amebiasis, acute pelvic inflammatory disease, Legionnaire’s disease, pertussis, and syphilis.