Do endothelial cells come from bone marrow?
Endothelial progenitor cells (EPCs) are thought to originate from the bone marrow, mobilize in response to ischemia, and home to sites of vascular injury.
What is murine bone marrow?
Bone marrow-derived macrophages (BMDM) are primary macrophages obtained by in vitro differentiation of bone marrow cells in the presence of macrophage colony-stimulating factor (M-CSF or CSF1). They are easy to obtain in high yields, can be stored by freezing, and can be obtained from genetically modified mice strains.
What is murine hematopoietic stem cells?
Hematopoietic stem cells (HSCs) are a rare population in adult bone marrow (BM) and give rise to all lymphoid, myeloid, and erythroid cells. These are also expressed on other types of BM cells, and not all are conserved between species or during development.
Are epithelial cells in bone marrow?
With current techniques, epithelial-like cells can be detected in the bone marrow of many patients not known to have cancer.
What does the word murine mean?
Definition of murine : of or relating to a murid genus (Mus) or its subfamily (Murinae) which includes the common household rats and mice also : of, relating to, or involving these rodents and especially the house mouse.
What is a murine macrophage?
Macrophages are mononuclear phagocytes that are widely distributed throughout the body. These cells can contribute to development and homeostasis and participate in innate and adaptive immune responses.
Is bone marrow connective tissue?
Bone marrow is the soft, flexible connective tissue within bone cavities. A component of the lymphatic system, bone marrow functions primarily to produce blood cells and to store fat.
What is epithelial tissue?
What is the epithelium? The epithelium is a type of body tissue that forms the covering on all internal and external surfaces of your body, lines body cavities and hollow organs and is the major tissue in glands.
What do endothelial cells do in inflammation?
Endothelial cells are major participants in and regulators of inflammatory reactions. Resting endothelial cells prevent coagulation, control blood flow and passage of proteins from blood into tissues, and inhibit inflammation.