Is dysgerminoma a cancer?
A dysgerminoma is a type of germ cell tumor; it usually is malignant and usually occurs in the ovary….
| Dysgerminoma | |
|---|---|
| Specialty | Oncology, gynecology |
Is dysgerminoma cancer curable?
This treatment produces less morbidity than chemotherapy and will cure approximately two-thirds of patients. Chemotherapy should be used for salvage of subsequent relapse. Both radiation and chemotherapy are highly effective treatment modalities for dysgerminoma.
Is dysgerminoma ovarian cancer?
Dysgerminoma: This is the most common type of malignant ovarian germ cell tumor. Mature teratoma (dermoid cyst or ovarian cyst): This is the most common type of benign ovarian germ cell tumor. These noncancerous tumors usually grow in teenage girls and young women.
What causes dysgerminoma?
The exact etiology of dysgerminomas has not been determined, although molecular studies have implicated loss of function with potential tumor suppressor gene TRC8/RNF139 as a possible cause. Additionally, 5% of all dysgerminomas occur in dysgenetic gonads and may be associated with gonadoblastomas.
Can dysgerminoma come back?
Ovarian dysgerminoma is a rare type of germ cell tumor. The majority of patient relapses occur within 2 years of diagnosis.
What does dysgerminoma mean?
(DIS-jer-mih-NOH-muh) A type of cancer that begins in germ cells in females. Germ cells are cells that form sperm in males or eggs in females. Dysgerminomas occur most often in the ovaries, but they may also occur in other areas of the body, including the central nervous system.
What causes ovarian dysgerminoma?
The main neoplasms in the differential diagnosis of ovarian dysgerminoma are lymphoma/leukemia, yolk sac tumor, embryonal carcinoma, and Sertoli cell tumor. Large-cell lymphomas typically occur bilaterally.
What is dysgerminoma of the ovary?
What is the treatment for germ cell tumor?
Most patients with a cancerous germ cell tumor will need chemotherapy. The drugs that are commonly used for treating germ cell tumors include bleomycin (available as a generic drug), cisplatin (available as a generic drug), etoposide (Etopophos), and ifosfamide (Ifex).
What is the tumor marker for dysgerminoma?
Serum lactic dehydrogenase: a tumor marker for dysgerminoma.
Can germ cell tumors be cured?
Some germ cell tumors may be treated with radiation therapy alone or in combination with surgery. Chemotherapy is very effective for malignant germ cell tumors and is almost always used in combination with surgery. With the exception of relatively few germ cell tumors in children, cure rates are 90 percent or higher.
Which is raised in dysgerminoma?
Serum lactic dehydrogenase (LDH) levels are known to be elevated in some patients with dysgerminoma.